Publications

EL. Kennedy, M. Jeon, F. Augustine, KM. Chauhan, S. An, and M. Kyoung  “Functional regulation of 4D metabolic network between multienzyme glucosome condensates and mitochondria” bioRxiv, 2022

H-W. Kang*, L. Nguyen, S. An, and M. Kyoung*  “Mechanistic insights of glucosome condensate formation by stochastic modeling approaches” (2022) under revision

A. Pedley, J. Boylan, CY. Chan, EL. Kennedy, M. Kyoung; SJ. Benkovic “Purine biosynthetic enzymes assemble into liquid-like condensates dependent on the activity of chaperone protein HSP90” JBC, accepted. 2022

M. Jeon ,  DL. Schmitt, M. Kyoung , and S. An “Functional oscillation of a multienzyme glucosome assembly during cell cycle progression” bioRxiv, 2022

S. An*, P. Parajuli, EL. Kennedy, M. Kyoung* “Multi-dimensional Fluorescence Live-cell Imaging for Glucosome Dynamics in Living Human Cells” Methods in Molecular Biology, accepted, 2021

S. An*, M. Jeon, EL. Kennedy, M. Kyoung* “Phase-separated condensates of metabolic complexes in living cells: Purinosome and glucosome” Methods in Enzymology, 2019; 628, https://doi.org/10.1016/bs.mie.2019.06.013 

C. Kohnhorst^†, M. Kyoung^†, M Jeon, DL. Schmitt, EL. Kennedy, J Ramirez, SM. Bracey, BT Luu, SJ. Russell, and S. An “Identification of a Multienzyme Metabolic Complex for Glucose Metabolism in Living Cells” JBC; 2017; 292, 9191-9203

M. Kyoung, S. Russell, C. Kohnhorst, N, Esemoto, S. An “Dynamic architecture of the purinosome involved in human de novo purine biosynthesis” Biochemistry; 2015; 54, 870-880

J. Diao, J. Burré, S. Vivona, D. Cipriano, M. Sharma, M. Kyoung, T. C. Südhof, A. T. Brunger ”α-Synuclein induces synaptic vesicle clustering via binding to phospholipids and Synaptobrevin-2/VAMP2” eLife; 2013; 2, e00592

J. Diao, M. Zhao, Y. Zhang, M. Kyoung, A. T. Brunger “Studying protein-reconstituted proteoliposome fusion with content indicators in vitro” BioEssays; 2013; 35, 658-665.

M. Kyoung, Y. Zhang, J. Diao, S. Chu, A. T. Brunger “Studying calcium-triggered vesicle fusion in a single vesicle-vesicle content and lipid-mixing system” Nature Protocols; 2013; 8, 1-16.

Diao, P. Grob, D. J. Cipriano, M. Kyoung, Y. hang, S. Shah, A. Nguyen, M. Padolina, A. Srivastava, M. Vrljic, A. Shah, E. Nogales, S. Chu, A. T. Brunger “Synaptic proteins promote calcium-triggered fusion from point contract to full fusion” eLife; 2012; 1, e00109.

F. Verrier, S. An, A. M. Ferrie, H. Sun, M. Kyoung, H. Deng, Y. Fang, S. J. Benkovic, “GPCR signaling regulates the assembly of a multienzyme complex for purine biosynthesis” Nature chemical biology, 2011; 7, 909-915.

M. Kyoung, A. Srivastava, Y. Zhang, M. Vrljic, P. Grob, E. Nogales, S. Chu, A. T. Brunger “Ca²⁺-triggered single vesicle content mixing: fast fusion kinetics reveals mechanistic insights into neurotransmitter release” Proc Natl Acad Sci U S A. 2011; 108 (29): E304-13.

• Research highlighted from Nature Methods : Nature Methods 2011 vol. 8, 708–709 (http://www.nature.com/nmeth/journal/v8/n9/full/nmeth.1685.html?WT.ec_id=NMETH-201109)
• Commentary from PNAS: ”Inside insight to membrane fusion” by Geert van den Bogaart and Reinhard Jahn. PNAS 2011 vol. 108 11729-11730 (http://www.pnas.org/content/108/29/11729.full )
• 20 most-read papers online during the month of July 2011 
• HHMI Bulletin :”When membranes merge ”Lab Book Soptlight November 2o11 p43 (http://www.hhmi.org/bulletin/nov2011/pdf/nov2011_fulltext.pdf)
• Recommended by Faculty of 1000 (http://f1000.com/12007956 )

S. An, Y. Deng, J. W. Tomsho, M. Kyoung, and S. J. Benkovic “Microtubule-assisted mechanism for functional metabolic macromolecular complex formation” Proc Natl Acad Sci U S A., 2010, 285, 12871-12876.

S. An, M. Kyoung, J. J. Allen, K. M. Shokat, S. J. Benkovic “Dynamic regulation of a metabolic multi-enzyme complex by protein kinase CK2” Journal of Biological Chemistry, 2010, 285, 11093-11099.

M. Kyoung, E. D. Sheets “Vesicle diffusion close to a membrane: intermembrane interactions measured with fluorescence correlation spectroscopy” Biophysical Journal, 2008, 95, 5789-5797.

K. Vats, M. Kyoung, E. D. Sheets “Characterizing the chemical complexity of patterned biomimetic membranes” Biochimica et Biophysica Acta, 2008, 1778, 2461-2468.

M. Kyoung, K. Karunwi, E. D. Sheets “A versatile multi-mode microscope to probe and manipulate nanoparticles and biomolecules” Journal of Microscopy, 2007, 225, 137-146.

M. Kyoung, E. D. Sheets, “Manipulating and probing the spatio-temporal dynamics of nanoparticles near surfaces” Proceedings of SPIE, 2006, 6326, 63262L.

M. Kyoung, S. Y. Kim, H. Y. Seok, I. S. Park, M. Lee, “Probing the caspase-3 active site by fluorescence lifetime measurements” Biochimica et Biophysica Acta, 2002, 29, 74-79.

M. Kyoung, M. Lee, “ Z-scan studies on the third-order optical nonlinearity of Au nanoparticles embedded in TiO₂.” Bulletin of the Korean Chemical Society, 2002, 21, 26-28.

M. Kyoung, M. Lee, “ Nonlinear absorption and refractive index measurements of silver nanorods by the Z-scan technique.” Optics Communications, 1999, 171, 145-148.